Polycystic kidney disease

This is the most common genetic disease in cats. Polycystic kidney disease (PKD) is characterized by the development of cysts in the kidneys. It invariably progresses to chronic kidney failure. The affected cat experiences excessive thirst and urination, vomiting, and weight loss. This disease is irreversible, and unfortunately, there is no cure. Veterinary care can alleviate symptoms and improve the animal's quality of life. The gene and its mutation (PKD1) can now be detected through DNA testing. Cats with PKD should be excluded from breeding.

Hypertrophic cardiomyopathy

This heart disease is characterized by a thickening of the heart walls.

The symptoms are similar to heart failure. The purebred cat will exhibit respiratory problems, a rapid heart rate, coughing, fatigue, and cyanosis (blue mucous membranes). The cat may also become paralyzed. This is due to thromboembolism (the formation of a blood clot).

An electrocardiogram and other tests are necessary to confirm the diagnosis, establish appropriate medical treatment, and implement a new lifestyle. Without veterinary care, the cat can suffer cardiac arrest. DNA testing makes it easier to identify carrier cats.

Progressive retinal atrophy

Progressive retinal atrophy (PRA) is a genetic disease that affects a cat's vision. It can lead to progressive blindness in felines. An ophthalmological examination of the back of the eye can detect it. Unfortunately, there is currently no cure. However, PRA can be identified through a DNA test.